Current Grants & Projects

NIH R01 NS110169
Pitts (PI) Howland (Co-I)

2018-2023

Regulation of swallow and the effects of high cervical spinal cord injury

 The long-term goal is to provide pre-clinical information on use of serotonin mediators in the treatment of dysphagia following cervical spinal cord injury

NIH R01 HL155721-
Bolser & Morris (MPI)
Pitts (Co-I)

2020-2024

Influence of opioids on the brainstem respiratory network

The long-term goal is the understand the central regulation of the breathing, alterations with opioids, and creation of a predictive computational model.

NIH R01 HL163008
Bolser, Morris & Pitts (MPI)

2022-2026

Central and peripheral regulation of laryngeal adduction

The long-term goal is the understand the central regulation of the laryngeal adductor reflex, alterations in the reflex with opioids, and creation of a predictive computational model.

NIH R21 HD110951
Pitts & Mellen (MPI)

6th percentile 

Delineating impacts of gestational opioid exposure on central swallow networks 

NIH R01 NS131607
Pitts (PI) Howland (Co-I)

Submitted June 2022

Serotonin receptor activation as therapeutic intervention for dysphagia following spinal cord injury

 

Completed 

 

Craig H. Neilsen Foundation CNF546714

2018-2020-Pitts (PI)

Regulation of airway protective reflexes with serotonin agonists


The long-term goal of this project is to understand the mechanisms of upper airway dysfunction after cervical spinal cord injury and to test a FDA approved 5HT1a agonist for treatment efficacy.

R01 HL 131716

2016-2020 -Bolser & Morris (MPI; Pitts, Co-I)

Modeling the role of the NTS in the neurogenesis of airway defensive behaviors


The long-term goal of this project is to develop a data-driven computational model of the brainstem network controlling breathing and cough since both behaviors share common downstream neural elements.

OT2 TR 001983 & 023854

2016-2020- Bolser (PI; Pitts, Co-I)

Functional mapping of peripheral and central circuits for airway protection and breathing


This is part of the NIH SPARC program, and the long-term goal is to understand fundamental principles of modulation and plasticity in afferent pathways, brain networks and efferent systems controlling breathing and airway defense.

K99/R00 HL 111215

2013-2018 -Pitts (PI)

Regulation of airway protective behaviors


The long-term goal of this project is to determine the role of tracheal and pharyngeal sensory feedback in the regulation of cough and swallow.

R21 HD 090752

2016-2018 -Smith, BK (PI; Pitts, Consultant)

Diaphragm pacing and rehabilitation in Pompe disease


The overall goal of this project was to conduct the first systematic evaluation of the impact of diaphragm pacing on the timing, synchrony, and activation of phrenic motor units in Pompe disease.

ASHF New Investigators Research Grant

2016-2017 -King (PI; Pitts, Mentor)

Characterization of radiation induced pharyngeal mucosa fibroses after head and neck cancer

UF Opportunity Fund

2013-2014 -Bolser (PI; Pitts, Co-I)

An External Device for Rehabilitation of Airway Protective Behaviors 


The long-term goal of this project was to develop a portable electrical simulation device for treatment of dysphagia.